Catalogue number: A664500
Chemical name: 6-Anilino-5,8-quinolinedione
Synonyms: 6-Anilinoquinoline-5,8-quinone; 5,8-Dihydro-5,8-dioxo-6-(phenylamino)quinoline; 6-(phenylamino)-5,8-quinolinedione; LY 83583;
CAS Number: 91300-60-6
Possible CAS #: NA
Molecular form.: C₁₅H₁₀N₂O₂
Appearance: Red-Brown Solid
Melting Point: 184-185°C
Mol. Weight: 250.25
Storage: -20˚C Freezer
Solubility: Dichloromethane
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Nitric Oxide Reagents
Boiling Point: No Data Available
Applications: Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2µM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release.
Dangerous Goods Info: NA
References: Macleod, K.M., et al.: Mol. Pharmacol., 32, 59 (1987), Mulsch, A. J.: J. Pharmacol. Exp. Ther., 247, 283 (1988), Mulsch, A., et al.: Naunyn-Schmiedeberg’s Arch. Pharmacol., 340, 119 (1989), Light, D.B., et al.: Science, 243, 383 (1989), Beasley, D., et al.: J. Clin. Invest., 87, 602 (1991)
Peer Review Product Citations:

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10mg $75.00
50mg $230.00
  Pack size Price(USD)
5mg $60.00
25mg $125.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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