Andrographolide

Catalogue number: A637475
Chemical name: Andrographolide
Synonyms: (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; [1R-[1α[E(S*)],4aβ,5α,6α,8aα]]-3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; 3α,14,15,18-Tetrahydroxy-5β,9βH,10α-labda-8(20),12-dien-16-oic Acid γ-Lactone; Andrographis; Andrographolid
CAS Number: 5508-58-7
Possible CAS #: NA
Molecular form.: C₂₀H₃₀O₅
Appearance: White Solid
Melting Point: 232-235°C
Mol. Weight: 350.45
Storage: Refrigerator
Solubility: DMSO
Stability: No Data Available
Category: Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Andrographolide is a labdane diterpenoid (2). Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata (2). Andrographolide showed significant antihepatotoxic action in P. berghei K173-induced hepatic damage in M. natalensis(1). Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases (2). These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
50mg $45.00
?
250mg $65.00
?
1g $135.00
?
  Pack size Price(USD)
100mg $50.00
?
500mg $85.00
?
5g $475.00
?
Exact Weight Packaging ($75(USD) / Vial)
?
Inventory Status:   Pending QC

Search Products:

Enter Catalogue #, CAS # , Chemical Name or Mol Formula:

Search By Category

Search By Category View products by category
Translate »