Aminopterin-α-hyrazide

Catalogue number: A628855
Chemical name: Aminopterin-α-hyrazide
Synonyms: N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic Acid 5-Hydrazide
CAS Number: 118359-33-4
Possible CAS #: NA
Molecular form.: C₁₉H₂₂N₁₀O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 454.44
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amino Acids & Derivatives, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Aminopterin-α-hyrazide, is derivative of Aminopterin (A628850), which is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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