2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester Monohydrochloride

Catalogue number: A622640
Chemical name: 2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester Monohydrochloride
Synonyms: 2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester Hydrochloride (1:1); T1032 N-Oxide
CAS Number: 260414-73-1
Possible CAS #: NA
Molecular form.: C₃₂H₃₀ClN₃O₈
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 620.05
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Enzyme substrates, Heterocycles, Inhibitors
Boiling Point: No Data Available
Applications: 2-(4-Aminophenyl)-1,2-dihydro-7-[(1-oxido-2-pyridinyl)methoxy]-1-oxo-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid methyl Ester Monohydrochloride, is a selective metabolite that is generated by cytochrome P450 3A5 (CYP3A5) oxidation of A622635.These compounds are also 4-Aryl-1-isoquinolinone Derivatives, which are shown to be novel, potent, and selective Phosphodiesterase 5 (PDE5) Inhibitors.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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