4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide

Catalogue number: A612095
Chemical name: 4-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide
Synonyms: MS 436;
CAS Number: 1395084-25-9
Possible CAS #: NA
Molecular form.: C₁₈H₁₇N₅O₃S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 383.42
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds,
Boiling Point: No Data Available
Applications: MS 436 is a potent bromodomain inhibitor, binding to BRD4 and more tightly to subdomain BD1 than BD2. These domains play a key role in inflammatory gene expression, mitosis and viral/host interaction. Applications involving innhibition of bromodomains include decrease in cell proliferation for leukemia and destruction of tumor cells.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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