1-(2-Amino-5-hydroxyphenyl)propan-1-one

Catalogue number: A611480
Chemical name: 1-(2-Amino-5-hydroxyphenyl)propan-1-one
Synonyms: 2’-Amino-5’-hydroxypropiophenone; AHPP
CAS Number: 35364-15-9
Possible CAS #: NA
Molecular form.: C₉H₁₁NO₂
Appearance: Brownish Yellow Solid
Melting Point: >138°C (dec.)
Mol. Weight: 165.19
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Miscellaneous Reagents
Boiling Point: No Data Available
Applications: 1-(2-Amino-5-hydroxyphenyl)propan-1-one is a useful synthetic intermediate. It is used in the asymmetrical synthesis of (S)-4-ethyl-6,7,8,10- tetrahydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione, a key intermediate for synthesis of irinotecan and other camptothecin analogs. It is also used in the synthesis of E-​ring-​modified (RS)​-​camptothecin analogs as antitumor agents.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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