4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide Hydrochloride

Catalogue number: A609735
Chemical name: 4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide Hydrochloride
Synonyms:
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₅H₂₀ClF₂N₅O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 527.91
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Impurities
Boiling Point: No Data Available
Applications: 4-(4-Amino-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide Hydrochloride is an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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