(2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester

Catalogue number: A609705
Chemical name: (2R,5S)-5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester
Synonyms: Emtricitabine Menthyl Ester
CAS Number: 764659-72-5
Possible CAS #: NA
Molecular form.: C₁₈H₂₆FN₃O₄S
Appearance: Off-White Solid
Melting Point: 190-192°C
Mol. Weight: 399.48
Storage: Refrigerator
Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Carbohydrates & Derivatives, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: An intermediate in the synthesis of Emtricitabine (E525000). A reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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