Catalogue number: A608790
Chemical name: 4-(2-Aminoethyl)benzenesulfonamide
Synonyms: p-(2-Aminoethyl)benzenesulfonamide; 2-(4-Sulfamoylphenyl)ethylamine; 2-[4-(Aminosulfonyl)phenyl]ethylamine; 4-(2-Aminoethyl)benzensulfonamide; 4-(Aminosulfonyl)phenethylamine; 4-Sulfamoylphenethylamine; p-(β-Aminoethyl)benzenesulfonamide; p-Aminoethyl-benzenesulfonamide
CAS Number: 35303-76-5
Possible CAS #: NA
Molecular form.: C₈H₁₂N₂O₂S
Appearance: White Solid
Melting Point: 147-149ºC
Mol. Weight: 200.26
Storage: Refrigerator, under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Miscellaneous Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: 4-(2-Aminoethyl)benzenesulfonamide is used as the starting material in the synthesis of Des(5-methylpyrazinecarbonyl) trans-4-Methyl Glipizide (D292605); a degradation product of Glimepiride (G410150) which is a sulfonylurea hypoglycemic agent and an antidiabetic. 4-(2-Aminoethyl)benzenesulfonamide is also used as a reagent in the synthesis of deorphaning pyrrolopyrazines as potent multi-target antimalarial agents.
Dangerous Goods Info: NA
References: Ratheiser, K., et al.: Arzneim.-Forsch., 43, 856, (1993); Bansal, G., et al.: J. Pharmaceut. Biomed., 43, 788 (2008); Reker, D., et al.: Angew. Chem. Int. Edit., 53, 7079 (2014)
Peer Review Product Citations:

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