Catalogue number: A602085
Chemical name: (E)-3-(4-Amino-3,5-bis(methoxymethyl)phenyl)acrylonitrile
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₁₃H₁₆N₂O₂
Appearance: Light Yellow Solid
Melting Point: No Data Available
Mol. Weight: 232.28
Storage: No Data Available
Solubility: Dichloromethane, Ethyl Acetate, Methanol
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: (E)-3-(4-Amino-3,5-bis(methoxymethyl)phenyl)acrylonitrile is an intermediate in the synthesis of 2,6-Dihydroxymethyl Rilpivirine (D446615), which is an analog of Rilpivirine (R509800) a novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
Dangerous Goods Info: NA
References: Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001); Griffin, D. et al.: J. Am. Chem. Soc., 134, 13103 (2012);
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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