Agmatine Sulfate

Catalogue number: A426900
Chemical name: Agmatine Sulfate
Synonyms: N-(4-aminobutyl)guanidine Sulfate; NIH 11035
CAS Number: 2482-00-0
Possible CAS #: NA
Molecular form.: C₅H₁₆N₄O₄S
Appearance: White Solid
Melting Point: 231-233°C
Mol. Weight: 228.27
Storage: Room Temp
Solubility: Water
Stability: No Data Available
Category: Amines, Amino Acids & Derivatives, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: General Uses: Neuroprotective, CNS studies, Autism and depression research Description: Agmatine Sulfate is a polyamine derived from L-arginine (A769500) decarboxylation and is a known putative endogenous neurotransmitter at imidazoline receptors. Agmatine sulfate displaces clonidine at α2-adrenergic and at imidazoline receptors and was recently shown to exert some neuroprotective effects. It blocks NMDA-receptor associated cation channels. Acts as a competitive inhibitor of nitric oxide synthase (NOS). It functions as neurotransmitter since it is stored in synaptic vesicles and is related from axon terminals by depolarization(1). Protects autistic behavior in rats (2) and reverses depressive like behavior in mice. (3)
Dangerous Goods Info: NA
References: PMID: 10785653
PMID: 27638451
PMID: 27743829
Peer Review Product Citations:

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Inventory Status:   Pending QC

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