Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (Contained ~8.5% Ethanol)

Catalogue number: A355320
Chemical name: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (Contained ~8.5% Ethanol)
Synonyms: N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine; Des(4-dimethylamino-2-en-1-oxo)butyl Afatinib
CAS Number: 314771-76-1
Possible CAS #: NA
Molecular form.: C₁₈H₁₆ClFN₄O₂
Appearance: Dark Yellow Solid
Melting Point: 183-186°C
Mol. Weight: 374.8
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Heterocycles
Boiling Point: No Data Available
Applications: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl is a reactant in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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