AF 12198

Catalogue number: A355020
Chemical name: AF 12198
Synonyms: N-​Acetyl-​L-​phenylalanyl-​L-​α-​glutamyl-​L-​tryptophyl-​L-​threonyl-​L-​prolylglycyl-​L-​tryptophyl-​L-​tyrosyl-​L-​glutaminyl-​(2S)​-​2-​azetidinecarbonyl-​L-​tyrosyl-​L-​alanyl-​L-​leucyl-​L-​prolyl-L-​Leucinamide
CAS Number: 185413-30-3
Possible CAS #: NA
Molecular form.: C₉₆H₁₂₃N₁₉O₂₂
Appearance: White to Off-White Solid
Melting Point: >206°C (dec.)
Mol. Weight: 1895.12
Storage: Refrigerator
Solubility: DMSO, Water (Sparingly)
Stability: No Data Available
Category: Peptides
Boiling Point: No Data Available
Applications: AF 12198 is a peptide that selectively binds Interleukin-1 (IL-1) receptor and blocks in vivo responses to IL-1 (1). The interleukin-1 receptor can activate the innate immune response by binding to cytokines (2). Dysregulation of cytokine production can lead to aberrant immune cells activation that could result in auto-inflammatory disorders.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $110.00
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25mg $1775.00
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  Pack size Price(USD)
5mg $475.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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