AEE 788-d5

Catalogue number: A325602
Chemical name: AEE 788-d5
Synonyms: 6-[4-[(4-(Ethyl-d5)-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine; [6-[4-[(4-(Ethyl-d5)piperazin-1-yl)methyl]phenyl]-7H-pyrrolo [2,3-d]pyrimidin-4-yl]-((R)-1-phenylethyl)amine; NVP-AEE 788-d5;
CAS Number: 1292840-54-0
Possible CAS #: 497839-62-0-unlabelled
Molecular form.: C₂₇H₂₇D₅N₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 445.61
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Chiral Reagents, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Boiling Point: No Data Available
Applications: Labelled AEE 788. A novel dual receptor tyrosine kinase inhibitor of the EGF and the VEGF receptor, for treatment of human HCC cell lines and in a s.c. xenograft model.
Dangerous Goods Info: NA
References: Ito, Y., et al.: Br. J. Cancer., 84, 1377 (2001), Huether, A., et al.: Biochem. Pharmacol., 70, 1568 (2005), Zhu, A., et al.: J. Clin. Oncol. 24, 1898 (2006), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),
Peer Review Product Citations:

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