Catalogue number: A291560
Chemical name: Aderbasib
Synonyms: (6S,7S)-7-[(Hydroxyamino)carbonyl]-6-[(4-phenyl-1-piperazinyl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylic Acid Methyl Ester; INCB 007839;
CAS Number: 791828-58-5
Possible CAS #: NA
Molecular form.: C₂₁H₂₈N₄O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 416.47
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Aderbasib is a azaspiro[2.5]octanehydroxamide derivative as inhibitor of metalloproteases for the treatment of disorders such as cancer, arthritis, cardiovascular or skin disorders.
Dangerous Goods Info: NA
References: Kuipers, W., et al.: J. Med. Chem., 38, 1942 (1995), Molina, M.A., et al.: Clin. Cancer Res., 8, 347 (2002), Moss, M.L., et al.: Biochemistry, 43, 7227 (2004),
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