Catalogue number: A179045
Chemical name: 1-Acetyl-4-(4-hydroxyphenyl)piperazine
Synonyms: 1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone; 4-(4-Acetylpiperazino)phenol; 1-Acetyl-4-(p-hydroxyphenyl)piperazine; Ketoconazole Intermediate (branched chain of ketoconazole)
CAS Number: 67914-60-7
Possible CAS #: NA
Molecular form.: C₁₂H₁₆N₂O₂
Appearance: White to Off-White Solid
Melting Point: 181-183°C
Mol. Weight: 220.27
Storage: -20°C Freezer
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo.
Dangerous Goods Info: NA
References: Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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