Abiraterone Isopropyl Ether-d7

Catalogue number: A108532
Chemical name: Abiraterone Isopropyl Ether-d7
Synonyms: 3-((3S,8R,9S,10R,13S,14S)-3-Isopropoxy-d7-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pyridine
CAS Number: NA
Possible CAS #: Unlabelled CAS# N/A
Molecular form.: C₂₇H₃₀D₇NO
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 398.63
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Impurities, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Boiling Point: No Data Available
Applications: Abiraterone Isopropyl Ether-d7 is the labeled analog of Abiraterone Isoproply Ether (A108532), an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.
Dangerous Goods Info: NA
References: Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389 (2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)
Peer Review Product Citations:

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